As Disintegrating agent: Kyron T has a very high swelling tendency of hydration either in contact with water or G.I. fluids causing fast disintegration without. Article | The purpose of present study was to compare Kyron T with other superdisintegrants and optimize the fast dissolving tablet of. industry to mask the taste of bitter medicine to achieve stability and drugs. It is white to off white fine powder, swellable in water. KYRON T is derived from.

Author: Nizil Keramar
Country: Nicaragua
Language: English (Spanish)
Genre: Photos
Published (Last): 9 March 2008
Pages: 330
PDF File Size: 8.95 Mb
ePub File Size: 9.54 Mb
ISBN: 918-5-60591-858-3
Downloads: 45005
Price: Free* [*Free Regsitration Required]
Uploader: Dijas

FTIR spectra of the crospovidone, Kyron T, physical blend and co-processed mixture of superdisintegrants in ratio of 1: Fast-melting tablets based on highly plastic granules. Formulation design and optimization of mouth dissolve tablets of nimesulide using vacuum drying technique Mukesh GohelMadhabhai M. Handbook of Pharmaceutical Excipients. Kyron T breaks the tablets into very smaller particles, thus it increases the effective surface area for the absorption of the active substances and thus it increases the dissolution and bioavailability of the active substances.

Gangurde Department of Pharmaceutics, K.

The flow prpoperties were shown in Table 3. Mouth dissolving tablets of aceclofenac were prepared by wet granulation technique using KYRON T as superdisintegrant and menthol as subliming agent. The prepared tablets were evaluated for physical parameters such as hardness, thickness, diameter, friability, weight variation, in vitro dispersion time, in vitro disintegration time, wetting time and water absorption ratio.

A quantity of powder equivalent to 10 mg of metoclopramide hydrochloride was extracted in pH 6. Orodispersible tablets ODTsalso known as fast melt, quick melts, fast disintegrating have the unique property of disintegrating in the mouth in seconds without chewing and the need of water.


Subscribe to our Newsletter All our latest content delivered to your inbox. Aceclofenac in the management of inflammatory pain. Owing to these features, we have been able to serve industries like Pharmaceutical, Nutracuetical and Cosmetic Industries. Showing of 21 references. Lyron quantity is from 2. The bulk density was determined as the ratio of weight to the volume of sample.

Required quantity is from 0. Hausner ratio is equal to the ratio of the tapped density to bulk density [ 11 ].

Search Import Export Data of India

Pilot study of relative bioavailability of two oral formulations of ketoprofen 25 mg in healthy subjects. This indicates that the drug release process is first order in nature. Product Description As Disintegrating agent: Email this article Login required.

Number of Employees to People. From This Paper Figures, tables, and topics from this paper. Thus kyrkn of two superdisintegrants with wicking and swelling properties leads to kygon rapid disintegration of tablets in contact with saliva within few seconds and also serves as a multifunctional excipient [ 9 ].

Disintegration time is of much importance in formulation of melt-inmouth tablets which was found to be in the range of 5. Formulation of a convenient dosage form for administration and achievement of better patient compliance are the two most important criteria in novel drug delivery t-14 [ 1 ]. It was noted as wetting time. I agree to the terms and privacy policy.


Nature of Business Exporter. Co-processed excipients exhibited improved functionality as compared to their physical mixtures [ 7 ].

Kyron T – View Specifications & Details by Corel Pharma Chem, Ahmedabad | ID:

Cumulative percent drug released was calculated and kinetic study models like zero-order and first-order were applied [ 15 ]. Dietary Potassium Search for additional papers on this topic. View Contact Call Seller Now. These are manufactured using high quality basic material which is t-134 from reliable vendors.

Export Data and Price of kyron t | Zauba

Preparation and evaluation of mouth dissolving tablets of salbutamol sulphate. In comparison to direct compression tablets containing the physical blends of crospovidone and Kyron T, a faster drug release was observed from the tablets made from coprocessed superdisintegrants which might be attributed to increased porosity. Abstract Orodispersible tablets ODTsalso known as fast melt, quick melts, fast disintegrating have the unique property of disintegrating in kyronn mouth in seconds without chewing and the need of kyrpn.

Showing of 2 extracted citations.

By clicking accept or continuing to use the site, you agree to the terms outlined in our Privacy PolicyTerms of Serviceand Dataset License. The flow properties were graded as per the USP specifications [ 15 ]. Required quantity is from 2.